Domain

Glycoside hydrolase, family 49, N-terminal domain (IPR023226)

Short name: Glyco_hydro_49_N_dom

Domain relationships

None.

Description

O-Glycosyl hydrolases (EC:3.2.1.) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [PMID: 7624375, PMID: 8535779]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site.

Dextranase (EC:3.2.1.11) and isopullulanase (EC:3.2.1.57) are members of glycoside hydrolase family 49 (GH49). Dextranase hydrolyses alpha-1,6-glycosidic bonds in dextran polymers.

The N-terminal domain of these enzymes forms a beta-sandwich structure that is similar to the immunoglobulin fold but contains two extra strands. [PMID: 18155243, PMID: 12962629].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam