Domain

Hepatocyte nuclear factor 1, dimerisation domain (IPR023219)

Short name: HNF1_dimer_dom

Domain relationships

None.

Description

The N-terminal dimerisation domain of the transcriptional activator hepatocyte nuclear factor 1 is essential for DNA binding and association of the transcriptional coactivator, DCoH (dimerization cofactor of HNF-1). This domain forms a unique four-helical bundle which is largely conserved when dimerisation occurs [PMID: 11106484].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SUPERFAMILY