Family

Mucin-1 (IPR023217)

Short name: Mucin-1

Family relationships

None.

Description

Mucins are high molecular weight glycoconjugates. Their ability to form gels means that they are a principle componant of most metazoan gel-like secretions. Most mucins are secreted onto mucosal surfaces, or as part of saliva. The proteins are characterised by two regions: a cysteine-rich N and C terminus, with a large central region consisting of tandem repeats. The repeats have a high number of serine or threonine residues, which become saturated with O- and N-linked oligosaccharides. Mucin overexpression occurs in, for example, several adenocarcinomas and disorders of the lungs such as as asthma, COPD and cystic fibrosis.

This entry represents the mucin-1 family of proteins.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
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