Homologous Superfamily

Mycolic acid cyclopropane synthase-like domain superfamily (IPR023143)

Short name: Cyclopro_synthase-like_dom_sf

Overlapping entries


Some bacteria synthesise betaine from glycine by a three-step methylation process. The first enzyme, glycine/sarcosine N-methyltransferase, leads to the formation of either sarcosine or N,N-dimethylglycine, which is further methylated to yield betaine (N,N,N-trimethylglycine) by the action of sarcosine/dimethylglycine N-methyltransferase. Both of these enzymes can catalyse the formation of N,N-dimethylglycine from sarcosine [PMID: 12466265].

This superfamily represents a helix hairpin domain found in several putative sarcosine-dimethylglycine methyltransferases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.