Homologous Superfamily

HP0242-like superfamily (IPR023126)

Short name: HP0242-like_sf

Overlapping entries


This domain superfamily is found in proteins of unknown function related to HP0242. The crystal structure of HP0242, a hypothetical protein from Helicobacter pylori (Campylobacter pylori) has been determined. It reveals an acid-adaptive protein possibly of physiological significance when H. pylori colonises the human stomach. The protein adopts a unique four alpha-helical triangular conformations. The biologically active form is thought to be a tetramer. The gene exist in an operon along with 6 other genes where the gene products appear to be related to iron storage and haem biosynthesis [PMID: 16395670].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.