Mevalonate kinase, archaeal (IPR022937)

Short name: Mevalonate_kinase_arc

Overlapping homologous superfamilies

Family relationships


Mevalonate kinase (EC: is well-characterised among the Eukaryotes, where it plays a role in the synthesis of isopentanyl pyrophosphate, a common intermediate for a number of pathways including cholesterol biosynthesis. It is also involved in mevalonate catabolism. Close homologues are found in the Archaea. A bacterial example is found in the Borrelia burgdorferi (Lyme disease spirochete), but is not necessarily the same biosynthetic enzyme.

This entry represents archaeal mevalonate kinases. The function of this enzyme is to catalyse the following reaction:

ATP + (R)-mevalonate = ADP + (R)-5-phosphomevalonate

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004496 mevalonate kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.