Family

RNA pyrophosphohydrolase RppH (IPR022927)

Short name: RppH

Family relationships

None.

Description

This entry represents an RNA pyrophosphohydrolase belonging to the nudix hydrolase family, RppH subfamily. It accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [PMID: 18202662].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
CDD
  • cd03671 (Ap4A_hydrolase_plant_like)
HAMAP