Flap endonuclease Xni (IPR022895)

Short name: Xni

Overlapping homologous superfamilies

Family relationships


This entry contains flap endonuclease Xni (also known as YgdG), which was previously identified as a 3'-5' exonuclease and named exonuclease IX (exonuclease 9) [PMID: 9592142, PMID: 9840179]. However, later on, Xni was found to possess flap endonuclease activity, but not exonuclease activity [PMID: 17567612, PMID: 19000038, PMID: 23821668]. It cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment [PMID: 23821668].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0048256 flap endonuclease activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.