Family

NAD(P)H-quinone oxidoreductase subunit D/H (IPR022885)

Short name: NDH1_su_D/H

Family relationships

Description

NAD(P)H-quinone oxidoreductase or NAD(P)H dehydrogenase 1 subunit D shuttles electrons from NADH, via FMN and iron-sulphur (Fe-S) centres, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. It couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

This subunit is known as subunit H in chloroplasts and cyanobacteria. In chloroplasts NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulphur (Fe-S) centres, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. In cyanobacteria NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulphur (Fe-S) centres, to quinones in the respiratory and/or the photosynthetic chain.The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.

This subunit often appears as a fusion of subunits C and D.

GO terms

Biological Process

GO:0055114 oxidation-reduction process

Molecular Function

GO:0016651 oxidoreductase activity, acting on NAD(P)H

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
TIGRFAMs
HAMAP