DNA polymerase IV (IPR022880)

Short name: DNApol_IV

Family relationships



DNA polymerase IV is a poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. It copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. It exhibits no 3'-5' exonuclease (proofreading) activity and may be involved in translesional synthesis [PMID: 9391106, PMID: 11080171, PMID: 11463382, PMID: 11751576, PMID: 12060704].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003887 DNA-directed DNA polymerase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.