Alginate lyase (IPR022859)

Short name: Alginate_lyase

Overlapping homologous superfamilies

Family relationships



This entry represents alginate lyase or poly (beta-D-mannuronate) lyase. It depolymerises alginate by cleaving the beta-1,4 glycosidic bond.

Alginate is a family of 1-4-linked copolymers of beta-D-mannuronic acid (M) and alpha-L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyse the depolymerisation of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end [PMID: 9683471]. Two subfamilies of alginate lyase exist: the poly(beta-D-mannuronate) lyase, EC:, and the poly(alpha-L-guluronate) lyase, EC:

GO terms

Biological Process

GO:0042122 alginic acid catabolic process

Molecular Function

GO:0045135 poly(beta-D-mannuronate) lyase activity

Cellular Component

GO:0042597 periplasmic space

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.