Actin interacting protein 3-like, C-terminal (IPR022782)

Short name: AIP3-like_C

Overlapping homologous superfamilies


Domain relationships


This entry represents the C-terminal domain of actin interacting protein 3 (also known as Bud6 in budding yeasts). Bud6 is an actin- and formin-interacting protein. The N-terminal half of Bud6 is a microtubule binding domain required for its localisation and for its function in cortical capture of astral microtubule ends. The C-terminal half (residues 489-788) directly facilitates actin filament assembly by the formin Bni1 and is required for NPF (nucleation-promoting factor) activity. The domain represented in this entry (residues 365-776) is overlapped with the C-terminal half of Bud6 in this study [PMID: 23161908]. This entry also includes proteins from animals.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.