Family

Dynein family light intermediate chain (IPR022780)

Short name: Dynein_light_int_chain

Overlapping homologous superfamilies

None.

Family relationships

Description

This entry consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organisation, and function of centrosomes and mitotic spindles when bound to pericentrin [PMID: 10545494, PMID: 10893222]. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organisation by binding cytoplasmic dynein 2 to its Golgi-associated cargo [PMID: 11907264].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam