Family

Dynein family light intermediate chain (IPR022780)

Short name: Dynein_light_int_chain

Family relationships

Description

This entry consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organisation, and function of centrosomes and mitotic spindles when bound to pericentrin [PMID: 10545494, PMID: 10893222]. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organisation by binding cytoplasmic dynein 2 to its Golgi-associated cargo [PMID: 11907264].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam