Apolipoprotein M (IPR022734)

Short name: ApoM

Overlapping homologous superfamilies

Family relationships



ApoM is a 25 kDa plasma protein associated with high-density lipoproteins (HDLs). ApoM is important in the formation of pre-ss-HDL and also in increasing cholesterol efflux from macrophage foam cells [PMID: 18490703]. Lipoproteins consist of lipids solubilized by apolipoproteins. ApoM lacks an external amphipathic motif and is uniquely secreted to plasma without cleavage of its terminal signal peptide [PMID: 18460466].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.