SARS coronavirus, polyprotein cleavage domain PL2pro (IPR022733)

Short name: Nsp3_PL2pro

Overlapping homologous superfamilies

Domain relationships



This domain is found in SARS and bat coronaviruses, and is about 70 amino acids in length. PL2pro is a domain of the non-structural protein nsp3, found associated with various other coronavirus proteins due to the polyprotein nature of most viral translation. The domain performs three of the cleavages required to separate the translated polyprotein into its distinct proteins [PMID: 12927536].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004197 cysteine-type endopeptidase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.