Protein SCAI (IPR022709)

Short name: SCAI

Overlapping homologous superfamilies


Family relationships


SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 [PMID: 19350017].

GO terms

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

GO:0003714 transcription corepressor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.