Family

Long-chain fatty acyl-CoA thioesterase, Rv0098-like (IPR022598)

Short name: FcoT_ThioEstase_Rv0098-like

Family relationships

None.

Description

Proteins in this family have a HotDog fold. This family was formerly known as DUF2662. The structure of Rv0098 from M. tuberculosis [PMID: 17524985] suggested a thioesterase function. Assays showed that this protein was a thioesterase with a preference for long chain fatty acyl groups [PMID: 17524985]. The maximal Kcat was observed for palmitoyl-CoA, although longer and shorter molecules were also cleaved. In solution this protein forms a homo-hexameric complex.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
Pfam