Domain

Neuropilin, C-terminal (IPR022579)

Short name: Neuropilin_C

Domain relationships

None.

Description

This domain of unknown function is located in the C terminus of the eukaryotic neuropilin receptors. There are two completely conserved residues (Y and E) that may be functionally important.

Neuropilins are essential multifunctional vertebrate cell surface receptors [PMID: 23116416]. They function as receptors for axon guidance factor semaphorin class 3 (Sema3), vascular endothelial growth factor (VEGF) and placenta growth factor-2 (PLGF-2).

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam