Family

18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like (IPR022238)

Short name: Bud23

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents 18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23 [PMID: 18332120]. Bud23 homologues can be found from yeast to human. They are S-adenosyl-L-methionine-dependent methyltransferases that specifically methylates the N7 position of a guanine in 18S rRNA [PMID: 25851604]. Bud23 homologue in Arabidopsis, known as Rid2 (ROOT INITIATION DEFECTIVE 2), is also involved in pre-rRNA processing [PMID: 21401745].

In humans, Bud23 is located in the Williams-Beuren syndrome (WBS) critical region [PMID: 11978965].

GO terms

Biological Process

GO:0070476 rRNA (guanine-N7)-methylation

Molecular Function

GO:0016435 rRNA (guanine) methyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam