Peptidase S8A, tripeptidyl peptidase II, arthropoda (IPR022232)

Short name: Peptidase_S8A_TPPII_art

Overlapping homologous superfamilies


Domain relationships



This entry represents a region of approximately 190 amino acids in length and is found in association with PF00082. The members are serine peptidases belonging to MEROPS peptidase family S8A, tripeptidyl peptidase II (TPPII), clan SB. They are a crucial component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. It is an amino peptidase belonging to the subtilase family removing tripeptides from the free N terminus of oligopeptides.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.