Family

Polo kinase kinase (IPR022165)

Short name: PKK

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This domain family is found in eukaryotes, and is approximately 140 amino acids in length. The family is found in association with PF00069. Polo-like kinase 1 (Plx1) is essential during mitosis for the activation of Cdc25C, for spindle assembly, and for cyclin B degradation. This family is Polo kinase kinase (PKK) which phosphorylates Polo kinase and Polo-like kinase to activate them. PKK is a serine/threonine kinase.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004674 protein serine/threonine kinase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam