Domain

SBF1/SBF2 domain (IPR022096)

Short name: SBF1/SBF2

Domain relationships

None.

Description

This domain family is found in eukaryotes, and is approximately 220 amino acids in length. It is found in association with PF02141, PF03456, PF03455. It is found is the middle region of SBF1 and SBF2, members of the myotubularin family. Myotubularin-related proteins have been suggested to work in phosphoinositide-mediated signalling events that may also convey control of myelination. Mutations of SBF2 are implicated in Charcot-Marie-Tooth disease [PMID: 12554688].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam