FAM69, protein-kinase domain (IPR022049)

Short name: FAM69_kinase_dom

Overlapping homologous superfamilies


Domain relationships



This is the C-terminal region of a family of FAM69 proteins from Metazoa and Viridiplantae that are active protein-kinases. The family members have a short transmembrane helix close to the N terminus, and thereafter are highly enriched with cysteines. FAM69 proteins are localised to the endoplasmic reticulum. Many members also have a short EF-hand, calcium-binding, domain just upstream of the kinase domain. The exact function of the more N-terminal family is uncertain.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.