Prohormone convertase enzyme (IPR022005)

Short name: Proho_convert

Overlapping homologous superfamilies


Domain relationships



This domain family is found in eukaryotes, and is approximately 40 amino acids in length. The family is found in association with PF01483, PF00082. There are two completely conserved residues (Y and D) that may be functionally important. This protein is the C-terminal domain of a prohormone convertase enzyme which targets hormones in dense core secretory granules. This C-terminal tail domain is the domain responsible for targeting these dense core secretory granules. The domain adopts an alpha helical structure [PMID: 19376969].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.