Domain

UHRF1, tandem tudor domain (IPR021991)

Short name: TTD_dom

Domain relationships

None.

Description

TTD, tandem tudor domain within UHRF1 preferentially binds H3 histone tails trimethylated at Lys-9. It specifically recognises H3 tail peptides with the heterochromatin-associated modification state of trimethylated lysine 9 and unmodified lysine 4 (H3K4me0/K9me3) [PMID: 14741369, PMID: 21489993].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam