Domain

D domain of beta-TrCP (IPR021977)

Short name: Beta-TrCP_D

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

This entry represents the D domain of beta-TrCP, which is a member of the WD40 class of F box proteins, and functions as a ubiquitin ligase. The D domain of these F box proteins is involved in mediating dimerisation of the protein [PMID: 17574027]. Dimerisation is necessary to polyubiquitinate substrates, so this D domain is vital in directing substrates towards the proteasome for degradation.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0046983 protein dimerization activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
SMART
Pfam