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Overview
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Cross-references
Domain
D domain of beta-TrCP (IPR021977)
Short name: Beta-TrCP_D
Overlapping homologous superfamilies
None.
Domain relationships
None.
Description
This entry represents the D domain of beta-TrCP, which is a member of the WD40 class of F box proteins, and functions as a ubiquitin ligase. The D domain of these F box proteins is involved in mediating dimerisation of the protein [PMID: 17574027]. Dimerisation is necessary to polyubiquitinate substrates, so this D domain is vital in directing substrates towards the proteasome for degradation.
GO terms
Biological Process
No terms assigned in this category.
Molecular Function
GO:0046983 protein dimerization activity
Cellular Component
No terms assigned in this category.