Domain

DNA/RNA tunnel of bacterial DNA dependent RNA polymerase (IPR021975)

Short name: RNApol_Rpb2_rif

Domain relationships

None.

Description

This domain is part of the beta subunit of bacterial DNA dependent RNA polymerase. This domain is the binding site for the antibacterial drug rifampin (and its analogues) which blocks the DNA/RNA tunnel and prevents initiation of transcription.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam