Domain

T cell CD4 receptor C-terminal region (IPR021963)

Short name: Tcell_CD4_Cterm

Domain relationships

None.

Description

This domain is the C-terminal domain of the CD4 T cell receptor. The C-terminal domain is the cytoplasmic domain which relays the signal for T cell activation. This process involves co-receptor internalisation. This domain is involved in binding to the N-terminal of Lck co-receptor in a Zn2+ clasp structure.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam