Protein of unknown function DUF3578 (IPR021961)

Short name: DUF3578

Family relationships



This entry represents a group uncharacterised proteins found in bacteria and archaea. Proteins in this family include 5-methylcytosine-specific restriction enzyme B (also known as mcrB) from E. coli. It recognises N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines) produced by a broad range of DNA methylases and appears to act against 5-methylcytosine preceded by a purine residue [PMID: 7781618].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.