SWI/SNF-like complex subunit BAF250/Osa (IPR021906)

Short name: BAF250/Osa

Overlapping homologous superfamilies


Family relationships


This entry represents the mammalian BAF250a/b and its homologue osa from fruit flies [PMID: 11124806]. They are part of the SWI/SNF-like ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling. In humans there are two BAF250 isoforms, BAF250a/ARID1a and BAF250b/ARID1b. BAF250a/b may be E3 ubiquitin ligases that target histone H2B [PMID: 20086098].

This entry also includes Arabidopsis LFR protein, which is involved in leaf and flower development [PMID: 18846319] and is required for the formation of anther cell layers and normal expression of genes that regulates anther development [PMID: 22461668].

GO terms

Biological Process

GO:0006338 chromatin remodeling

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0016514 SWI/SNF complex
GO:0035060 brahma complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.