Family

SWI/SNF-like complex subunit BAF250/Osa (IPR021906)

Short name: BAF250/Osa

Family relationships

Description

This entry represents the mammalian BAF250a/b and its homologue osa from fruit flies [PMID: 11124806]. They are part of the SWI/SNF-like ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling. In humans there are two BAF250 isoforms, BAF250a/ARID1a and BAF250b/ARID1b. BAF250a/b may be E3 ubiquitin ligases that target histone H2B [PMID: 20086098].

GO terms

Biological Process

GO:0006338 chromatin remodeling

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0090544 BAF-type complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam