SWI/SNF-like complex subunit BAF250/Osa (IPR021906)

Short name: BAF250/Osa

Family relationships


This entry represents the mammalian BAF250a/b and its homologue osa from fruit flies [PMID: 11124806]. They are part of the SWI/SNF-like ATP-dependent chromatin remodelling complex that regulates gene expression through regulating nucleosome remodelling. In humans there are two BAF250 isoforms, BAF250a/ARID1a and BAF250b/ARID1b. BAF250a/b may be E3 ubiquitin ligases that target histone H2B [PMID: 20086098].

This entry also includes Arabidopsis LFR protein, which is involved in leaf and flower development [PMID: 18846319] and is required for the formation of anther cell layers and normal expression of genes that regulates anther development [PMID: 22461668].

GO terms

Biological Process

GO:0006338 chromatin remodeling

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.