AMIN domain (IPR021731)

Short name: AMIN_dom

Overlapping homologous superfamilies


Domain relationships



This N-terminal domain of various bacterial protein families is crucial for the targetting of periplasmic or extracellular proteins to specific regions of the bacterial envelope. AMIN is derived from the N-terminal domain of AmiC, an N-acetylmuramoyl-l-alanine amidase of Escherichia coli which localises to the septal ring during division and plays a key role in the separation of daughter cells. The AMIN domain is present in several protein families besides amidases suggesting that AMIN may represent a general targetting determinant involved in the localisation of periplasmic protein complexes [PMID: 18723522].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.