Domain

Nucleolar pre-ribosomal-associated protein 1, N-terminal (IPR021714)

Short name: Npa1_N

Domain relationships

None.

Description

Nucleolar pre-ribosomal-associated protein 1 (Npa1) is required for ribosome biogenesis and operates in the same functional environment as Rsa3p and Dbp6p during early maturation of 60S ribosomal subunits [PMID: 15208443]. The protein partners of Npa1p include eight putative helicases as well as the novel Npa2p factor. Npa1p can also associate with a subset of H/ACA and C/D small nucleolar RNPs (snoRNPs) involved in the chemical modification of residues in the vicinity of the peptidyl transferase centre [PMID: 15226434]. The protein has also been referred to as Urb1.

This entry represents a domain is found at the N terminus of Npa1.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam