WD repeat binding protein EZH2 (IPR021654)

Short name: EZH2_WD-Binding

Family relationships



This family of proteins represents Enhancer of zest homologue 2, (EZH2) a 30 residue peptide which binds to a WD-repeat domain of EED by residues 39-68. EED is a component of PRC2 complex which is involved in gene expression [PMID: 17937919]. This interaction is required for the HMTase activity of PCR2 [PMID: 17937919].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0018024 histone-lysine N-methyltransferase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.