Domain

Syntaxin-5, N-terminal, Sly1p-binding domain (IPR021538)

Short name: Syntaxin-5_N

Domain relationships

None.

Description

This entry represents the Sed5 N-terminal and the N terminus of Syntaxin-5-like proteins. It is the region of Syntaxin that interacts with Sly1p, a positive regulator of intracellular membrane fusion, allowing SM (cytosolic Sec1/munc18-like) proteins to stay associated with the assembling fusion machinery. This allows the SM proteins to participate in late fusion steps [PMID: 12426383].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam