Family

N-terminal acetyltransferase A, auxiliary subunit (IPR021183)

Short name: NatA_aux_su

Family relationships

None.

Description

This entry represents N-terminal acetyltransferase A (NatA) auxiliary subunit, which is a non-catalytic component of the NatA N-terminal acetyltransferase that catalyses acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-terminal acetylation plays a role in normal eukaryotic translation and processing, protecting against proteolytic degradation and protein turnover. NAT1 anchors ARD1 and NAT5 to the ribosome, and may present the N terminus of nascent polypeptides for acetylation [PMID: 1600941, PMID: 14517307].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
PIRSF