Domain

Holliday junction recognition protein, HJURP (IPR021052)

Short name: HJURP

Domain relationships

None.

Description

Vertebral Holliday junction recognition proteins carry an SCM3 domain at their N terminus as do the eukaryotic fungi, but they also carry this central, conserved region. Further downstream there is also a repeated domain, also of unknown function. Investigation of Scm3 and associated proteins is likely to be directly relevant to understanding the mechanism of HJURP-mediated CENP-A chromatin assembly at human centromeres [PMID: 19410544, PMID: 19410545].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam