Domain

Complementary sex determiner, C-terminal (IPR021007)

Short name: Sex_determ_C

Overlapping homologous superfamilies

None.

Domain relationships

None.

Description

Sex determination proteins are found in eukaryotes. Proteins in this family are typically between 168 and 410 amino acids in length. It plays a role in the gender determination of around 20% of all animals.

In the honeybee, the mechanism of sex determination depends on the complementary sex determiner (csd) gene which produces an SR-type protein. Males are homozygous while females are homozygous for the csd gene. Heterozygosity generates an active protein which initiates female development [PMID: 15382141].

This entry represents the C-terminal end of the sex determination protein.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam