Complementary sex determiner, C-terminal (IPR021007)

Short name: Sex_determ_C

Overlapping homologous superfamilies


Domain relationships



Sex determination proteins are found in eukaryotes. Proteins in this family are typically between 168 and 410 amino acids in length. It plays a role in the gender determination of around 20% of all animals.

In the honeybee, the mechanism of sex determination depends on the complementary sex determiner (csd) gene which produces an SR-type protein. Males are homozygous while females are homozygous for the csd gene. Heterozygosity generates an active protein which initiates female development [PMID: 15382141].

This entry represents the C-terminal end of the sex determination protein.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.