Domain

Histone-arginine methyltransferase CARM1, N-terminal (IPR020989)

Short name: Histone-Arg_MeTrfase_N

Domain relationships

None.

Description

Histone-arginine methyltransferase CARM1 (also known as coactivator-associated arginine methyltransferase 1) methylates arginine residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability [PMID: 16146736]. CARM1 is recruited by several transcription factors and plays a critical role in gene expression as a positive regulator. This entry represents the N-terminal domain of CARM1. Structurally this domain adopts a PH domain-like fold, a common structural scaffold found in a broad range proteins with diverse activities, which is frequently found to regulate protein-protein interactions [PMID: 17882262].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam