Cell cycle regulatory protein Speedy (IPR020984)

Short name: Speedy

Family relationships



Speedy (Spy1) is a cell cycle regulatory protein which activates CDK2, the major kinase that allows progression through G1/S phase and further replication events. Spy1 expression overcomes a p27-induced cell cycle arrest to allow for DNA synthesis, so cell cycle progression occurs due to an interaction between Spy1 and p27 [PMID: 17671428]. Spy1 is also known as Ringo protein A.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.