Conserved Site

Phosphodiesterase YfcE, conserved site (IPR020935)

Short name: PdiEstase_YfcE_CS

Description

This entry represents a short conserved sequence region found in a family of short, hydrophilic proteins that are all known or suspected phosphodiestreases. The best characterised of these is YfcE from Escherichia coli [PMID: 17586769]. The physiological substrate for this protein is not known, though it is capable of hydrolysing phosphodiesters bonds in the artificial chromogenic substrate bis-p-nitrophenyl phosphate. YfcE is a tetrameric, managanese-binding protein where each monomer forms a beta-sandwich fold similar to other metallophosphatases.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns