Conserved Site

Uncharacterised protein family UPF0758, conserved site (IPR020891)

Short name: UPF0758_CS


This family was named initially with reference to the Escherichia coli radC102 mutation which suggested that RadC was involved in repair of DNA lesions [PMID: 11053371]. However the relevant mutation has subsequently been shown to be in recG, not radC [PMID: 10224240]. In addition all attempts to characterise a radiation-related function for RadC in Streptococcus pneumoniae failed, suggesting that it is not involved in repair of DNA lesions, in recombination during transformation, in gene conversion, nor in mismatch repair [PMID: 18556794].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns