Conserved Site

Imidazoleglycerol-phosphate dehydratase, conserved site (IPR020565)

Short name: ImidazoleglycerP_deHydtase_CS


Imidazoleglycerol-phosphate dehydratase is the enzyme that catalyses the seventh step in the biosynthesis of histidine in bacteria, fungi and plants. In most organisms it is a monofunctional protein of about 22 to 29 kD. In some bacteria such as Escherichia coli, it is the C-terminal domain of a bifunctional protein that include a histidinol-phosphatase domain [PMID: 3062174].

Both signature patterns in this entry cover two consecutive, conserved histidine residues.

GO terms

Biological Process

GO:0000105 histidine biosynthetic process

Molecular Function

GO:0004424 imidazoleglycerol-phosphate dehydratase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns