Family

Accessory cholera enterotoxin, Ace (IPR020495)

Short name: Accessory_cholera_enterotoxin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This entry represents an enterotoxin found in Vibrio cholerae and other Vibrio species. V. cholerae causes the disease cholera via the intestinal secretogen, cholera toxin. A second toxin, Zot, decreases intestinal tissue resistance by modifying intercellular tight junctions. A third, Ace, increases short-circuit current in Ussing chambers and causes fluid secretion in ligated rabbit ileal loops by increasing the potential difference [PMID: 8389476].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
ProDom
  • PD065768 (Accessory_cholera_enterotoxin)