Family

Interleukin-22 (IPR020453)

Short name: IL-22

Overlapping homologous superfamilies

Family relationships

None.

Description

Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells.

This entry represents Interleukin-22 (IL-22), that belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26 [PMID: 11929132]. It is produced by activated T cells and acts as a T cell mediator, promoting the innate, non-specific immunity of tissues [PMID: 15308104]. IL-22 also regulates early defence mechanisms against attaching and effacing (A/E) bacterial pathogens [PMID: 18264109].

This entry represents interleukin-22.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
PIRSF
PANTHER
Pfam