Transcription regulator HTH, AraC- type (IPR020449)

Short name: Tscrpt_reg_HTH_AraC-type

Overlapping homologous superfamilies


Family relationships


Numerous bacterial transcription regulatory proteins bind DNA via a helix-turn-helix (HTH) motif. These proteins are very diverse, but for convenience may be grouped into subfamilies on the basis of sequence similarity. One such family groups together a range of proteins, including aadA, appY, aracC, celD, envY, exsA, fapR, melR, mmsR, rhaR, rhaS, rns, soxS, tetD, virF and xylS [PMID: 1655713, PMID: 1339433, PMID: 1708380]. Although the sequences belonging to this family differ somewhat in length, in each case the HTH motif is situated towards the C terminus.

GO terms

Biological Process

GO:0006355 regulation of transcription, DNA-templated

Molecular Function

GO:0003700 DNA binding transcription factor activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.