Pathways & interactions
Maltose fermentation regulatory protein, DNA-binding domain (IPR020448)
Short name: Maltose_ferment_reg_DNA-bd
Overlapping homologous superfamilies
- Zn(2)-C6 fungal-type DNA-binding domain (IPR001138)
- Maltose fermentation regulatory protein, DNA-binding domain (IPR020448)
The N-terminal region of a number of fungal transcriptional regulatory proteins contains a Cys-rich motif that is involved in zinc-dependent binding of DNA. The region forms a binuclear Zn cluster, in which two Zn atoms are bound by six Cys residues [PMID: 2107541, PMID: 1557122]. A wide range of proteins are known to contain this domain. These include the proteins involved in arginine, proline, pyrimidine, quinate, maltose and galactose metabolism; amide and GABA catabolism; leucine biosynthesis, amongst others.
This entry represetns a subset of these domains found specifically in maltose fermentation regulatory protein. This protein regulates the transcription of structural MAL1S (maltase) and AGT1 (maltose permease) genes.
- PR00054 (FUNGALZNCYS)