Interleukin-24 (IPR020444)

Short name: IL-24

Overlapping homologous superfamilies

Family relationships


Interleukins (IL) are a group of cytokines that play an important role in the immune system. They modulate inflammation and immunity by regulating growth, mobility and differentiation of lymphoid and other cells.

Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26 [PMID: 11929132]. It has been proposed, based on the expression pattern of IL-24 and its receptors, that the cytokine may play a role in epidermal functions, such as wound healing [PMID: 15667561]. IL-24 has also been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent [PMID: 14508078].

This entry represents interleukin-24.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.