Family

Transcription regulator CaiF/GrlA (IPR020357)

Short name: Tscrpt_reg_CaiF/GrlA

Family relationships

None.

Description

This is a family of transcriptional regulators that includes CaiF and GrlA. CaiF is a specific carnitine-sensitive transcription regulator [PMID: 8631699]. CaiF and CRP, a cyclic AMP receptor protein, are required to activate the cai and fix operons, which are involved in anaerobic carnitine metabolism [PMID: 10564497]. GrlA is encoded within the LEE type III secretion system in the enteropathogenic E. coli O157:H [PMID: 24092262]. GrlR interacts with GrlA at its Helix-Turn-Helix (HTH) motif, preventing GrlA from binding to its target promoter DNA.

GO terms

Biological Process

GO:0006351 transcription, DNA-templated

Molecular Function

No terms assigned in this category.

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom
  • PD081346 (Transcription_activatory_CaiF)