Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Ost5 (IPR020294)

Short name: Ost5

Overlapping homologous superfamilies


Family relationships


Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Ost5 is an essential subunit of the N-oligosaccharyl transferase enzyme which catalyses the transfer of a high mannose oligosaccharide to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs co-translationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum. The oligosaccharyl transferase (OST) complex appears to exist in two assemblies comprising Ost1, Ost2, Ost4, Ost5, Stt3, Swp1, Wpb1, and either Ost3 or Ost6 [PMID: 18334218]. Ost1 and Ost5 probably form a subcomplex. Ma interact directly with Ost1, Ost2 and Ost4. All subunits are required for a maximal enzyme activity.

GO terms

Biological Process

GO:0006487 protein N-linked glycosylation

Molecular Function

No terms assigned in this category.

Cellular Component

GO:0008250 oligosaccharyltransferase complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
  • PD061703 (Oligosaccharyl_Trfase_su_OST5)