Family

Arginine vasopressin-induced protein 1/C8orf4 (IPR020282)

Short name: Avpi1/C8orf4

Family relationships

None.

Description

This entry includes arginine vasopressin-induced protein 1 (Avpi1) and C8orf4 protein. Avpi1 is thought to be involved in MAP kinase activation, epithelial sodium channel (ENaC) down-regulation and cell cycling [PMID: 12356727]. C8orf4 plays important roles in many signalling pathways, such as Wnt/beta-catenin signalling pathway, and is involved in the development of many cancers [PMID: 25869879]. C8orf4 also suppresses NOTCH2 signalling in liver cancer stem cells [PMID: 25985737].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
ProDom
  • PD287216 (Arg_vasopressin-induced_prot_1)